Para-nitroazaprocin

Para-nitroazaprocin
Legal status
Legal status	UK: Class A;
Identifiers
	IUPAC name 1-[3-[(E)-3-(4-nitrophenyl)prop-2-enyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one;
CAS Number	59038-10-7;
PubChem CID	9797552;
ChemSpider	7973318;
Chemical and physical data
Formula	C18H23N3O3
Molar mass	329.400 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)N1C2CCC1CN(C2)C/C=C/C3=CC=C(C=C3)[N+](=O)[O-];
	InChI InChI=1S/C18H23N3O3/c1-2-18(22)20-16-9-10-17(20)13-19(12-16)11-3-4-14-5-7-15(8-6-14)21(23)24/h3-8,16-17H,2,9-13H2,1H3/b4-3+; Key:WRILSPHRDWMEMQ-ONEGZZNKSA-N;

Para-nitroazaprocin is an opioid designer drug which is the 4'-nitro derivative of azaprocin. It has around 25x the potency of morphine,^[1] and was made a Class A drug in the UK in May 2024.^[2]

References

^ Cignarella G, Barlocco D, Tranquillini ME, Volterra A, Brunello N, Racagni G (May 1988). "Interaction of 3,8-diazabicyclo (3.2.1) octanes with mu and delta opioid receptors". Pharmacological Research Communications. 20 (5): 383–394. doi:10.1016/s0031-6989(88)80014-6. hdl:11380/1247742. PMID 2843931.
^ "Order 2024". The Misuse of Drugs Act 1971 (Amendment).

[1] Cignarella G, Barlocco D, Tranquillini ME, Volterra A, Brunello N, Racagni G (May 1988). "Interaction of 3,8-diazabicyclo (3.2.1) octanes with mu and delta opioid receptors". Pharmacological Research Communications. 20 (5): 383–394. doi:10.1016/s0031-6989(88)80014-6. hdl:11380/1247742. PMID 2843931.

[2] "Order 2024". The Misuse of Drugs Act 1971 (Amendment).

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