SCH-79687

SCH-79687
Names
Preferred IUPAC name
N-(3,5-Dichlorophenyl)-N′-({4-[(1H-imidazol-4-yl)methyl]phenyl}methyl)urea
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) checkY
    Key: CXNCQFJNXQAFND-UHFFFAOYSA-N checkY
  • InChI=1/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)
    Key: CXNCQFJNXQAFND-UHFFFAOYAC
  • Clc1cc(cc(Cl)c1)NC(=O)NCc2ccc(cc2)Cc3c[nH]cn3
Properties
C18H16Cl2N4O
Molar mass 375.251 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

SCH-79687 is a histamine antagonist selective for the H3 subtype.[1]

References

  1. ^ McLeod RL, Rizzo CA, West RE Jr, Aslanian R, McCormick K, Bryant M, Hsieh Y, Korfmacher W, Mingo GG, Varty L, Williams SM, Shih NY, Egan RW, Hey JA. Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687). Journal of Pharmacology and Experimental Therapeutics. 2003 Jun;305(3):1037-44. PMID 12649305 doi=10.1124/jpet.103.049254
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