List of entactogens
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This is a list of entactogens, or drugs that produce feelings of social connection and empathy.
Phenethylamines
Amphetamines
- 3-Chloromethamphetamine (3-CMA)
- 3-Methoxymethamphetamine (MMMA)
- 4-Fluoroamphetamine (4-FA)
- para-Methoxyamphetamine (PMA)
- 4-Methylthioamphetamine (4-MTA)
Methylenedioxyamphetamines (benzodioxoles)
- MMDA (5-methoxy-MDA)
- 5-Methyl-MDA
- Methylbenzodioxolylbutanamine (MBDB)
- Methylenedioxyamphetamine (MDA)
- Methylenedioxyethylamphetamine (MDEA)
- Methylenedioxymethamphetamine (MDMA)
- Methylenedioxyhydroxyamphetamine (MDOH)
- Lys-MDA
- Lys-MDMA
Benzofurans
- 6-(2-Aminopropyl)benzofuran (6-APB) (benzofury)
- 5-(2-Aminopropyl)benzofuran (5-APB)
- 5-(2-Methylaminopropyl)benzofuran (5-MAPB)
Others
- 5-APDI (indanylaminopropane; IAP)
- Methamnetamine (PAL-1046)
- SeDMA
- ODMA
- TDMA
Cathinones
- Mephedrone (4-MMC)
- 3-Methylmethcathinone (3-MMC, metaphedrone)
- Methylone (MDMC; βk-MDMA)
- Butylone (βk-MBDB)
- Flephedrone (4-FMC)
- TH-PVP
Psychedelic phenethylamines
Cyclized phenethylamines
2-Aminoindanes
- 5-Iodo-2-aminoindane (5-IAI)
- 5,6-Methylenedioxy-2-aminoindane (MDAI)
- 5,6-Methylenedioxy-N-methyl-2-aminoindane (MDMAI)
- 5-Methoxy-6-methyl-2-aminoindane (MMAI)
- 5-Methoxy-2-aminoindane (MEAI, 5-MeO-AI)
2-Aminotetralins
Aminorexes
- 4,4'-Dimethylaminorex (4,4'-DMAR)
- Methylenedioxy-4-methylaminorex (MDMAR)
Tryptamines
α-Alkyltryptamines
- α-Ethyltryptamine (αET)
- α-Methyltryptamine (αMT)
β-Keto-α-alkyltryptamines
Tryptamine bioisosteres
Isotryptamines
- α-Methylisotryptamine (isoAMT; PAL-569)
Indolizines
See also
- Serotonin releasing agent
- Substituted methylenedioxyphenethylamine
- List of investigational hallucinogens and entactogens
References
- ^ Luethi D, Liechti ME (April 2020). "Designer drugs: mechanism of action and adverse effects". Arch Toxicol. 94 (4): 1085–1133. Bibcode:2020ArTox..94.1085L. doi:10.1007/s00204-020-02693-7. PMC 7225206. PMID 32249347.
In one of the few clinical studies of a designer drug, 4-bromo-2,5-dimethoxyphenylethylamine (2C-B) was shown to induce euphoria, well-being, and changes in perception, and to have mild stimulant properties (Gonzalez et al. 2015). 2C-B may thus be classified as a psychedelic with entactogenic properties, an effect profile that is similar to various other phenethylamine psychedelics (Shulgin and Shulgin 1995).
- ^ Wills B, Erickson T (9 March 2012). "Psychoactive Phenethylamine, Piperazine, and Pyrrolidinophenone Derivatives". In Barceloux DG (ed.). Medical Toxicology of Drug Abuse: Synthesized Chemicals and Psychoactive Plants. Wiley. pp. 156–192. doi:10.1002/9781118105955.ch10. ISBN 978-0-471-72760-6.
DOSE EFFECT: Anecdotal data suggests that recreational doses of 2C-B range from 4—30 mg with lower doses (4—10 mg) producing entactogenic effects, whereas high doses (10— 20 mg) cause psychedelic and sympathomimetic effects.
- ^ González D, Torrens M, Farré M (2015-10-12). "Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions". BioMed Research International. 2015: 643878. doi:10.1155/2015/643878. PMC 4620274. PMID 26543863.