Jens Juul Holst

Jens Juul Holst
Born (1945-08-31) 31 August 1945
Copenhagen, Denmark
Alma materUniversity of Copenhagen
Scientific career
Fields
InstitutionsUniversity of Copenhagen

Jens Juul Holst (born 31 August 1945)[1] is a Danish physician and physiologist. He is known for discovering and describing the hormone glucagon-like peptide-1 (GLP-1), a hormone in the gut that plays an important role in the onset and development of Type 2 diabetes.[2] In collaboration with researcher and author Arne Astrup, he discovered that GLP-1 acts as a satiety hormone in humans.[3]

In 2020, he was awarded the Warren Alpert Foundation Prize along Daniel J. Drucker and Joel F. Habener.[4] In 2021, he was awarded the Canada Gairdner International Award along Daniel J. Drucker, Joel F. Habener, and Mary-Claire King.[5] He was also awarded the Banting Medal by the American Diabetes Association (ADA).[6] In 2024, he was awarded the Princess of Asturias Awards for Technical and Scientific Research along Daniel J. Drucker, Jeffrey M. Friedman, Joel F. Habener, and Svetlana Mojsov.[7]

In 2024, he received the Tang Prize in the category of "Biopharmaceutical Science",[8] and the BBVA Foundation Frontiers of Knowledge Award in the category "Biology and Biomedicine".[9] In 2025, he received the Breakthrough Prize in Life Sciences alongside Daniel Drucker, Joel Habener, Svetlana Mojsov, and Lotte Bjerre Knudsen).[10]

References

  1. ^ Vibeke Lyngklip Svansø (31 August 2015). "Forskeren, der opdagede et guldæg". Berlingske (in Danish).
  2. ^ Singh G, Krauthamer M, Bjalme-Evans M (January 2022). "Wegovy (semaglutide): a new weight loss drug for chronic weight management". Journal of Investigative Medicine. 70 (1): 5–13. doi:10.1136/jim-2021-001952. PMC 8717485. PMID 34706925.
  3. ^ Astrup, Arne (2024). "Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions". European Journal of Clinical Nutrition. 78 (7): 551–556. doi:10.1038/s41430-024-01460-6. ISSN 0954-3007. PMC 11230893. PMID 38890501.
  4. ^ Prize Recipients | Warren Alpert Foundation Prize
  5. ^ "2021 Canada Gairdner Awards Recognize World-Renowned Scientists For Transformative Contributions To Research Impacting Human Health". 7 April 2021. Retrieved 13 December 2021.
  6. ^ "Exceptional Leaders in Diabetes Research, Prevention and Treatment to be Recognized at ADA's 81st Scientific Sessions" (PDF; 269 kB). diabetes.org. American Diabetes Association. 2021-03-08.
  7. ^ "Daniel J. Drucker, Jeffrey M. Friedman, Joel F. Habener, Jens Juul Holst, and Svetlana Mojsov, Princess of Asturias Award for Technical and Scientific Research 2024". Princess of Asturias Foundation. 5 June 2024.
  8. ^ Tang Prize 2024
  9. ^ BBVA Foundation Frontiers of Knowledge Award 2024
  10. ^ "Breakthrough Prize – Breakthrough Prize Announces 2025 Laureates in Life Sciences, Fundamental Physics, and Mathematics". breakthroughprize.org. Retrieved 2025-05-01.