Henry John Klassen

Henry John Klassen is an American physician-scientist in the field of regenerative ophthalmology, known for his research in stem cell treatments for retinal disorders, such as retinitis pigmentosa (RP).

Early life and education

Klassen received a BA in neurobiology from the University of California at Berkeley.[1] He earned his medical degree in 1991 and his PhD in neurobiology in 1998 from the University of Pittsburgh School of Medicine.[2] He finished his internship at Cambridge Hospital (Massachusetts) and Harvard Medical School, then went on to an Ophthalmology residency at the Yale Eye Center. After that, he undertook a combined fellowship in London, which involved clinical training in medical retina with Professor Alan C. Bird at Moorfields Eye Hospital and research with Professor Raymond Lund at the Institute of Ophthalmology.[3]

Academic and professional career

After completing his fellowship, Klassen was a senior stem cell researcher at the Children's Hospital of Orange County, where he researched retina-derived stem cells.[4][5] He then moved to the Singapore Eye Research Institute before joining the Department of Ophthalmology at the University of California, Irvine (UCI), where he works as a professor. He is also the director of the Stem Cell and Regeneration Program at UCI.[6] On 2012, Klassen co-founded jCyte,[7] a biotech firm focused on creating Stem-cell therapy for retinal disorders. As the company's president, he guides efforts to translate research from the lab to clinical applications.[8]

Research focus

Klassen's lab focuses on the practical application of human retinal progenitor cells (hRPCs) as treatment options for degenerative retinal conditions, especially retinitis pigmentosa. His studies have demonstrated that the transplantation of retinal progenitor cells can enhance photoreceptor function in deteriorating retinas. The stem cell treatment jCell, created by jCyte, has received Orphan drug status from both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This status allows the company to access several advantages, such as protections for intellectual property, tax benefits, and funding opportunities. Furthermore, jCell has been included in the Therapeutics for Rare and Neglected Diseases (TRND) program, which is affiliated with the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH).[9]

Academic Distinctions

  • B.A. degree with Distinction in General Scholarship, 1979
  • Pittsburgh Neuroscience Society Annual Award for Excellence in Basic Science Research, 1987
  • Citation for Excellence in Research, University of Pittsburgh School of Medicine, 1989
  • Outstanding Presentation of the 1989 Eastern Student Research Forum
  • Certificate of Recognition for Excellence in Medical Student Research, AMA, 1989
  • Yale Alumni in Ophthalmology Resident Research Prize, 1994
  • Career Development Award, Foundation Fighting Blindness, 1997 Appointments
  • Ph.D., Neurobiology, Anatomy and Cell Science, University of Pittsburgh, 1989[2]
  • Innovator Awards, Awarded Entrepreneurial Leader of the Year 2023[10]

Personal life

On 15 March 2024, Klassen converted to Islam, stating that the perseverance of the people of Gaza inspired his decision.[11][12]

See also

References

  1. ^ "Mary Kazanecki fiancee of Henry John Klassen". Citizens' Voice. 1988-09-05. p. 28. Retrieved 2025-06-01 – via Newspapers.com.
  2. ^ a b "Henry John Klassen". University of California, Irvine. 5 November 2020.
  3. ^ "Henry Klassen, M.D., Ph.D." UCI stem cell research center.
  4. ^ Ornstein, Charles; Mestel, Rosie (2001-08-10). "Bush decision draws critics on both sides". The Los Angeles Times. p. 173. Retrieved 2025-06-01 – via Newspapers.com.
  5. ^ "Will the 21st century bring new eyes for the blind?". The Wasatch Wave. 2004-06-02. p. 17. Retrieved 2025-06-01 – via Newspapers.com.
  6. ^ Cohn, Meredith (2016-02-19). "She can see, and stem cells may be why". The Baltimore Sun. pp. A1A15. Retrieved 2025-06-01 – via Newspapers.com.
  7. ^ "Powered by CIRM Grant, jCyte Launches New Clinical Trial for RP". Global Genes. 4 May 2017.
  8. ^ jCyte Inc. (21 February 2024). "jCyte Inc. Announces Positive Pre-Phase 3". jCyte.
  9. ^ "jCyte Develops Treatment for Rare Eye Disease". innovation.uci.edu. 16 May 2017.
  10. ^ "Henry Klassen, M.D., Ph.D. Awarded Entrepreneurial Leader of the Year". 13 May 2024.
  11. ^ Kasraoui, Safaa (17 March 2024). "Famous Scientist Henry Klassen Converts to Islam".
  12. ^ "Famous Professor Henry Klassen MD Ph.D at Harvard University Has converted to islam". 17 March 2024.
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