Florence Comite

Florence Comite, MD
Comite in 2014
Born
Florence Comite
Occupation(s)Physician, endocrinologist
Employer(s)Comite Center for Precision Medicine & Healthy Longevity, Northwell Health[1]
Known forAssociate Clinical Professor Yale University School of Medicine
WebsiteOfficial website

Florence Comite is an American endocrinologist[2] and the leading female expert in the fields of healthy longevity and proactive precision medicine.

She is internationally known for reversing biological aging in her patients by treating each one as his or her own clinical trial—an Nof 1™—leveraging three decades of proprietary clinical data from her private clinical and virtual practices.

Dr. Comite trained as a clinical researcher at the National Institutes of Health and was a faculty member at her alma mater, Yale School of Medicine, for twenty-five years with a triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology). She founded the nation’s first medical clinic devoted exclusively to women—Women’s Health at Yale—in 1992.

Comite is known for having an integrated approach to proactive health care delivery using precision medicine. She has researched hormonal changes and aging, and in particular, issues of hypogonadism in men and low testosterone in women and how “low T” impacts the onset of such associated diseases as diabetes and heart disease.

In 1989, Comite was awarded a patent for developing a new method of determining fertility in women using Clomifene.[3] In 1990, Comite was awarded a second patent for the use of Clomifene to increase bone mass in premenopausal women.[4]

In 2005, Comite founded the Comite Center for Precision Medicine & Healthy Longevity in New York City, where she first established a clinically proven, academic approach to personalized healthcare structured around the individualized clinical process known as Nof 1™. In recent years, the Center has opened offices in Palo Alto and Miami Beach.

Field of study

Comite is known for practicing an integrated approach to health care delivery using precision medicine. She has published original research in numerous clinical journals, such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. She has also published seminal research in children, women, and men showing that we must analyze humans’ entire system at the cellular level to accurately diagnose and treat the disorders and diseases that are caused and exacerbated by aging.

Her research involves studying delivery systems and how they impact health outcomes; it has been her focus as a Senior Clinical and Research Adviser to the Offices of Alternative Medicine (OAM) at NIH.[5]

Education and early career

Comite graduated summa cum laude from Brooklyn College of the City University of New York Yale University School of Medicine; she was an associate clinical professor on the Yale faculty for 25 years; She founded Women's Health at Yale in 1988.[6] Comite completed a fellowship in Reproductive Endocrinology, incorporating training in Medicine, Pediatrics, Gynecology and Andrology,[7] at the National Institute of Child Health and Human Development at NIH. In early 1980, she was researching the use of Gonadotropin-releasing hormones to treat precocious puberty.[8][9]

Comite has significant research and clinical experience in complementary and alternative medicine (CAM).[10]

Comite has served on advisory councils and committees with the NIH, the Egyptian Ministry of Health, and on the Balance Documentary Medical Advisory Board,[11] the Age Management Medicine Group, Independent Doctors of New York,[12] and the American Fertility Society as well as Alpha Omega Alpha.[13]

Awards and Books

Alan P. Mintz, MD Award for Clinical Excellence in Age Management Medicine, 2013.[6]

Keep it Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life, Rodale Books, 2023.

Invincible: Defy Your Genetic Destiny to Live Healthier Longer, Little, Brown Spark, to be published, April 2026

References

  1. ^ "Florence Comite, MD". Northwell Health.
  2. ^ "Male Menopause Crisis Finds Solutions In Hormone Optimization Program". Red Orbit. April 24, 2007. Retrieved April 2, 2014.
  3. ^ Andrews, Edmund (April 29, 1989). "Patents; A Method to Determine Fertility in Women". New York Times. Retrieved April 2, 2014.
  4. ^ Yale, University. "Use of clomiphene to increase bone mass in premenopausal women '13 Nov 1990'". Justia Patents. Retrieved June 11, 2015.
  5. ^ "Late Nights with Jim Bohannon". The Jim Bohannon Show. December 13, 2013. Archived from the original on May 20, 2014. Retrieved May 19, 2014.
  6. ^ a b Curtis, John (December 11, 2013). "Florence Comite, M.D.'76, recognized for hormone research". Yale Alumni Journal. Retrieved April 2, 2014.
  7. ^ Urist, Jacoba (October 21, 2013). "Men Have Biological Clocks, Too". The Atlantic. Retrieved April 2, 2014.
  8. ^ Comite, Florence; Cutler, Gordon B.; Rivier, Jean; Vale, Wylie W.; Loriaux, D. Lynn; Crowley, William F. (December 24, 1981). "Short-Term Treatment of Idiopathic Precocious Puberty with a Long-Acting Analogue of Luteinizing Hormone-Releasing Hormone". New England Journal of Medicine. 305 (26): 1546–1550. doi:10.1056/NEJM198112243052602. PMID 6458765.
  9. ^ Sonis, William A; Florence Comite; ORA H. PESCOVITZ; KAREN HENCH; CHARLES W. RAHN; GORDON B. CUTLER Jr.; D L LORIAUX; ROBERT P. KLEIN (May 28, 1985). "Biobehavioral Aspects of Precocious Puberty". Journal of the American Academy of Child Psychiatry. 25 (5): 674–679. doi:10.1016/s0002-7138(09)60293-4. PMID 3760417.
  10. ^ Prevention, Committee on the Use of Complementary and Alternative Medicine by the American Public, Board on Health Promotion and Disease (2004). Complementary and alternative medicine in the United States ([Online-Ausg.] ed.). Washington, DC: National Academies Press. p. 321. ISBN 978-0-309-09270-8.{{cite book}}: CS1 maint: multiple names: authors list (link)
  11. ^ Richards, Avis. "Balance Documentary". Birds Nest Foundation. Archived from the original on April 7, 2014. Retrieved April 2, 2014.
  12. ^ "New York Superdoctors" (PDF). Independent Doctors of New York: IDNY.org. May 19, 2013. Archived from the original (PDF) on April 7, 2014. Retrieved April 2, 2014.
  13. ^ "Alpha Omega Alpha". Directory. Alpha Omega Alpha. Retrieved April 2, 2014.
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