Edith A. Perez

Edith A. Perez
Born
Alma materUniversity of Puerto Rico, Río Piedras Campus (BS)
University of Puerto Rico School of Medicine (MD)
Scientific career
InstitutionsMayo Clinic Alix School of Medicine

Edith A. Perez, M.D., is an internationally renowned hematologist-oncologist and thought leader committed to advancing cancer drug development and improving patient care through health equity and access to innovative treatments. Dr. Perez is a highly respected leader and role model for future generations, with over 700 peer-reviewed authored or co-authored manuscripts and abstracts [1], reflected by her frequent invitations to lecture at national and international meetings as well as serving on the board of multiple academic journals and holding leadership and advisory positions across academic, clinical, and industry settings, including Professor Emeritus at Mayo Clinic.

Early life and Education

Born in Humacao, Puerto Rico [2], Dr. Perez graduated magna cum laude with a B.S. in Biology from the University of Puerto Rico. Dr. Perez earned her medical degree at the University of Puerto Rico School of Medicine, San Juan, Puerto Rico and completed her residency in internal medicine at the Loma Linda University Medical Center, Loma Linda, CA [3]. Dr. Perez served in the National Health Service Corps for two years before completing a fellowship in hematology and oncology at the UC Davis School of Medicine [4]. Dr. Perez furthered her education by completing executive education programs at the Harvard Kennedy School and at the Wharton School of the University of Pennsylvania [1]. She is board certified in internal medicine, medical oncology, and hematology.

Industry Career

In 2025, Dr. Perez officially cemented her role at Cornerstone Specialty Network with acceptance of the role of Chief Medical Officer after serving as a Cornerstone medical advisory partner and key opinion speaker for several years [5]. As Chief Medical Officer, Dr. Perez plays a pivotal role in leading and expanding all Cornerstone Specialty Network’s clinical programs, evidence-based initiatives and collaborations with provider partners to empower community oncology practices and ultimately optimize patient care across the nation.

Prior to joining Cornerstone Specialty Network, Dr. Perez served as Chief Medical Officer at Bolt Biotherapeutics [6] (2020 – 2024) bringing her clinical and scientific expertise to direct the development of a novel immune-oncology pipeline [7]. Dr. Perez was Vice President of the BioOncology Medical Unit at Genentech [8] (2015 – 2018) as well as a member of the Oncology Commercial Leadership Team, where she led the successful development and launch of multiple practice-changing and life-changing oncology therapeutics, including GAZYVA®[9], PERJETA®[10], ALECENSA®[11], and TECENTRIQ®[12]. She was also a member of the Genentech/Roche Cancer Immunotherapy Governance Committee. Dr. Perez currently serves on scientific advisory committees for two early-stage biotech companies supporting their innovative efforts.

Academic Achievements

Throughout Dr. Perez’s 20+ year tenure at Mayo Clinic, she has distinguished herself in teaching, research and patient care, making profound contributions to the treatment of breast cancer and the advancement of translational biomarkers. She was granted a Mayo endowed professorship and rose to become Deputy Director at Large for the Mayo Clinic Cancer Center [13]. Global collaborations and funding from the National Cancer Institute (NCI) [14], the National Institutes of Health (NIH) [15], and leading foundations such as the Breast Cancer Research Foundation (BCRF) [16] have been integral to her career. While she was working at the Mayo Clinic, Dr. Perez was essential to the N9831 trial, which demonstrated the impact of adding trastuzumab to improve disease-free and overall survival for patients with early-stage HER-2 positive breast cancer [17]. The combination of chemotherapy and trastuzumab, as opposed to chemotherapy alone, improved the survival rate of patients by 33%, helping to save thousands of lives in the US and around the globe.

Board of Directors and Advocacy Work

Dr. Perez currently serves on the Board of Directors for the Food Allergy Research Foundation (FARE) [18][19] and the Puerto Rico Science, Technology & Research Trust (PRSTRT) [20][21]. Most recently Dr. Perez, as part of the committee on strategies to better align investments in innovations for therapeutic development with disease burden and unmet needs, published a consensus study report in the National Academies of Sciences, Engineering, and Medicine 2025 titled Aligning Investments in Therapeutic Development with Therapeutic Need: Closing the Gap. Washington, DC: The National Academies Press [22].

Over her career, Dr. Perez has been a member of multiple National Cancer Institute committees, including the Board of Scientific Advisors (BSA) and the Clinical Trials and Translational Committee (CTAC) [23]. She has been a member of five National Academies (NASEM) [24] Consensus Groups, contributing to groundbreaking reports including Improving Diversity Across the Clinical Trial and Research Ecosystem (2021-2023) [25] and Strategies to Better Align Investments in Innovations for Therapeutic Development with Disease Burden and Unmet Needs (2024-2025). Dr. Perez served on the Board of Directors of Artiva Biotherapeutics [26] (2022-2024) and has also been involved in diversity leadership and philanthropic initiatives with the American Society of Clinical Oncology (ASCO) and the American Association for Cancer Research (AACR), The DONNA Foundation [27], Stand Up to Cancer and the Komen Foundation [28].

Personal Life

In addition to her academic and biomedical industry pursuits, Dr. Perez co-founded [29] The National Marathon to Finish Breast Cancer [30] to raise funds for underserved women and genomics/immunologic translational cancer research. She runs it every year. More than 20,000 families have received assistance from the proceeds and more than $3.3M has been raised for cancer research [31]. The organization also operates events and programs for survivorship, education and awareness.

References

  1. ^ https://pubmed.ncbi.nlm.nih.gov/?term=Edith%20A.%20Perez
  2. ^ https://www.discoverpuertorico.com/regions/east/humacao#!grid~~~random~1
  3. ^ https://lluh.org/locations/loma-linda-university-medical-center
  4. ^ https://health.ucdavis.edu/medical-school/
  5. ^ https://www.cornerstoneoncology.com/provider-network-holdings-appoints-dr-edith-a-perez-m-d-as-chief-medical-officer-of-cornerstone-specialty-network/
  6. ^ https://www.boltbio.com/wp-content/uploads/2020/04/Bolt-Edith-Perez-CMO-release-FINAL.pdf
  7. ^ https://www.boltbio.com/
  8. ^ https://www.gene.com/
  9. ^ https://www.gazyva.com/
  10. ^ https://www.perjeta.com/
  11. ^ https://www.alecensa.com/
  12. ^ https://www.tecentriq.com/
  13. ^ https://www.mayoclinic.org/departments-centers/mayo-clinic-cancer-center
  14. ^ https://www.cancer.gov/
  15. ^ https://www.nih.gov/
  16. ^ https://www.bcrf.org/
  17. ^ https://www.nejm.org/doi/full/10.1056/NEJMoa052122
  18. ^ https://www.foodallergy.org/
  19. ^ https://www.foodallergy.org/about-us/fare-boards
  20. ^ https://prsciencetrust.org/
  21. ^ https://prsciencetrust.org/team/
  22. ^ https://nap.nationalacademies.org/catalog/29157/aligning-investments-in-therapeutic-development-with-therapeutic-need-closing-the
  23. ^ https://www.cancer.gov/about-nci/organization/ccct/ctac#:~:text=CTAC%20is%20an%20external%20oversight%20committee%20that%20advises,research%20enterprises%2C%20including%20both%20intramural%20and%20extramural%20research.
  24. ^ https://www.nationalacademies.org/
  25. ^ https://www.nationalacademies.org/en/event/08-24-2022/improving-diversity-across-the-clinical-trial-and-research-ecosystem
  26. ^ https://www.artivabio.com/
  27. ^ https://thedonnafoundation.org/
  28. ^ https://www.komen.org/
  29. ^ https://breastcancermarathon.com/donna-special-guests/
  30. ^ https://breastcancermarathon.com/
  31. ^ https://thedonnafoundation.org/