2024 Nobel Prize in Physiology or Medicine

The 2024 Nobel Prize in Physiology or Medicine
Ambros and Ruvkun: "for the discovery of microRNA and its role in post-transcriptional gene regulation"
Date7 October 2024 (2024-10-07)
LocationStockholm
CountrySweden
Presented byNobel Assembly at Karolinska Institutet
Reward(s)9 million SEK (2017)[1]
First award1901
2024 laureateVictor Ambros and Gary Ruvkun
Website2024 Nobel Prize in Physiology or Medicine

The 2024 Nobel Prize in Physiology or Medicine was awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation"[2] secretary of the Nobel Assembly at Karolinska Institutet in Stockholm, Sweden, on 7 October 2024.

Victor Ambros

This section is an excerpt from Victor Ambros.[edit]
Victor R. Ambros (born December 1, 1953) is an American developmental biologist who discovered the first known microRNA (miRNA). He is a professor at the University of Massachusetts Medical School. He completed both his undergraduate and doctoral studies at the Massachusetts Institute of Technology. Ambros received the Nobel Prize in Physiology or Medicine in 2024 for his research on microRNA.[3]

Gary Ruvkun

This section is an excerpt from Gary Ruvkun.[edit]

Ruvkun discovered the mechanism by which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing to those targets, and discovered the second miRNA, let-7, and that it is conserved across animal phylogeny, including in humans. These miRNA discoveries revealed a new world of RNA regulation at an unprecedented small size scale, and the mechanism of that regulation. Ruvkun also discovered many features of insulin-like signaling in the regulation of aging and metabolism.

He was elected a Member of the American Philosophical Society in 2019. Ruvkun was awarded the 2024 Nobel Prize in Physiology or Medicine for the discovery of microRNA and its role in post-transcriptional gene regulation.[4]

References

  1. ^ "Nobel Prize amount is raised by SEK 1 million". Nobelprize.org. Archived from the original on 1 February 2018. Retrieved 20 August 2022.
  2. ^ Nobel Prize Outreach. "The Nobel Prize in Physiology or Medicine 2024". NobelPrize.org. Retrieved 17 August 2025.
  3. ^ "Press release: The Nobel Prize in Physiology or Medicine 2024". NobelPrize.org. Archived from the original on October 8, 2024. Retrieved October 7, 2024.
  4. ^ "Press release: The Nobel Prize in Physiology or Medicine 2024". NobelPrize.org. Archived from the original on October 8, 2024. Retrieved October 7, 2024.
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