2022 Guanajuato Open – Singles

Singles
2022 Guanajuato Open
Champion	Zhu Lin
Runner-up	Rebecca Marino
Score	6–4, 6–1

Zhu Lin won the title, defeating Rebecca Marino in the final, 6–4, 6–1.

Astra Sharma was the defending champion having won the event when it was last held in 2019,^[1] but chose to participate at the BNP Paribas Open, where she reached the second round as a lucky loser.

	Semifinals							Final
	1	Zhu Lin	6	6
		Anastasia Tikhonova	2	0
								1	Zhu Lin	6	6
								2	Rebecca Marino	4	1
		Carolina Alves	5	1
	2	Rebecca Marino	7	6

	First round							Second round							Quarterfinals							Semifinals
	1	L Zhu	6	6
	Q	AP Martínez Mora	0	0				1	L Zhu	6	6
		D Vismane	4	1					Q Gleason	1	4
		Q Gleason	6	6											1	L Zhu	65	6	6
	Q	E Oosterhout	3	65											8	J Loeb	77	2	3
		K Volodko	6	77					K Volodko	4	77	4
		L Glushko	3	3				8	J Loeb	6	64	6
	8	J Loeb	6	6																		1	L Zhu	6	6
	LL	AM Becerra	6	61	63																		A Tikhonova	2	0
	WC	G Arangio	4	77	77			WC	G Arangio	1	1
		A Tikhonova	77	1	6				A Tikhonova	6	6
		F Contreras	64	6	2											A Tikhonova	6	6
	Q	D Hewitt	2	77	6										Q	D Hewitt	2	3
		M Zacarías	6	64	4			Q	D Hewitt	6	4	6
		F Di Lorenzo	6	6					F Di Lorenzo	3	6	4
	LL	S Schenck	0	0

	First round							Second round							Quarterfinals							Semifinals
	5	R Anderson	6	3	6
		A Sutjiadi	4	6	2			5	R Anderson	4	2
	Q	Z Hitt	2	0					C Alves	6	6
		C Alves	6	6												C Alves	4	77	6
	Q	E Douglas	77	6											Q	E Douglas	6	65	1
	Q	K Christian	62	2				Q	E Douglas	7	5	6
	WC	CS Martínez Solís	0	1				4	A Hartono	5	7	0
	4	A Hartono	6	6																			C Alves	5	1
	7	V Grammatikopoulou	6	2	6																	2	R Marino	7	6
		P Plipuech	2	6	1			7	V Grammatikopoulou	2	1
	Q	MF Navarro	4	2					S Mendez	6	6
		S Mendez	6	6												S Mendez	5	1
		W Osuigwe	78	6											2	R Marino	7	6
	Q	J Hinojosa Gómez	66	3					W Osuigwe	1	2
	SE	A Reami	3	3				2	R Marino	6	6
	2	R Marino	6	6

• Main Draw