2021 US Open – Wheelchair men's singles
| Wheelchair men's singles | |
|---|---|
| 2021 US Open | |
| Champion |  Shingo Kunieda |
| Runner-up |  Alfie Hewett |
| Score | 6–1, 6–4 |
Defending champion Shingo Kunieda[1] defeated Alfie Hewett in the final, 6–1, 6–4 to win the men's singles wheelchair tennis title at the 2021 US Open. It was his eighth US Open singles title and 25th major singles title overall.
Seeds
- Shingo Kunieda (champion)
- Alfie Hewett (final)
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- ITF = ITF entry
- PR = Protected ranking
- SR = Special ranking
- SE = Special exempt
- JE = Junior exempt
- JR = Junior Accelerator Programme entrant
- CO = College Accelerator Programme entrant
- NG = Next Gen Accelerator Program entrant
- w/o = Walkover
- r = Retired
- d = Defaulted
Finals
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Shingo Kunieda
| 6 | 6 | |||||||||||||||||
| WC |  Casey Ratzlaff
| 1 | 0 | |||||||||||||||||
| 1 | Shingo Kunieda
| 4 | 6 | 6 | ||||||||||||||||
| Gordon Reid
| 6 | 4 | 2 | |||||||||||||||||
 Tom Egberink
| 1 | 4 | ||||||||||||||||||
| Gordon Reid
| 6 | 6 | ||||||||||||||||||
| 1 | Shingo Kunieda
| 6 | 6 | |||||||||||||||||
| 2 | Alfie Hewett
| 1 | 4 | |||||||||||||||||
 Stéphane Houdet
| 4 | 3 | ||||||||||||||||||
 Gustavo Fernández
| 6 | 6 | ||||||||||||||||||
| Gustavo Fernández
| 2 | 4 | ||||||||||||||||||
| 2 | Alfie Hewett
| 6 | 6 | |||||||||||||||||
| Nicolas Peifer
| 5 | 2 | ||||||||||||||||||
| 2 | Alfie Hewett
| 7 | 6 | |||||||||||||||||