2021 Sardegna Open – Singles

Singles
2021 Sardegna Open
Champion	Lorenzo Sonego
Runner-up	Laslo Đere
Score	2–6, 7–6(7–5), 6–4
Draw	28
Seeds	8

Lorenzo Sonego defeated defending champion Laslo Đere in the final, 2–6, 7–6^(7–5), 6–4 to win the men's singles title at the 2021 Sardegna Open. With the victory, Sonego became the first Italian in 15 years to capture an ATP Tour title on home soil.

The top four seeds received a bye into the second round.

	Semifinals							Final
		Laslo Đere	6	6
	4	Nikoloz Basilashvili	2	0
									Laslo Đere	6	65	4
								3	Lorenzo Sonego	2	77	6
	3	Lorenzo Sonego	6	5	6
	2	Taylor Fritz	4	7	1

	First round							Second round							Quarterfinals							Semifinals
								1	D Evans	1	6	68
		L Musetti	6	6					L Musetti	6	1	710
		D Novak	0	1												L Musetti	4	6	2
	WC	F Gaio	4	2												L Đere	6	4	6
		L Đere	6	6					L Đere	6	6
		F Coria	65	6	3			6	J Millman	3	3
	6	J Millman	77	3	6																		L Đere	6	6
																						4	N Basilashvili	2	0
								4	N Basilashvili	4	6	7
	Q	S Nagal	6	1	3			Q	J Kovalík	6	4	5
	Q	J Kovalík	3	6	6										4	N Basilashvili	7	4	6
	Q	M-A Hüsler	1	3											5	J-L Struff	5	6	3
	Q	L Broady	6	6				Q	L Broady	4	2
		J Sousa	6	1	5			5	J-L Struff	6	6
	5	J-L Struff	1	6	7

	First round							Second round							Quarterfinals							Semifinals
	8	T Paul	68	7	3
		Y Hanfmann	710	5	6				Y Hanfmann	7	6
		M Cecchinato	6	4	6				M Cecchinato	5	1
	WC	T Fabbiano	4	6	3											Y Hanfmann	6	66	3
		G Simon	1	6	6										3	L Sonego	3	78	6
		S Travaglia	6	3	4				G Simon	4	1
								3	L Sonego	6	6
																						3	L Sonego	6	5	6
	7	G Pella	4	0																		2	T Fritz	4	7	1
		E Gerasimov	6	6					E Gerasimov	4	65
		A Bedene	1	7	77				A Bedene	6	77
	WC	G Zeppieri	6	5	63											A Bedene	3	4
		A Martin	6	2	6										2	T Fritz	6	6
		J Veselý	4	6	1				A Martin	2	64
								2	T Fritz	6	77

	First round							Qualifying competition
	1	Jozef Kovalík	6	6
		Malek Jaziri	3	1
								1	Jozef Kovalík	77	4	77
									Matteo Viola	63	6	64
		Matteo Viola	64	6	6
	5	Brandon Nakashima	77	1	2

	First round							Qualifying competition
	2	Cedrik-Marcel Stebe	6	6
		Matthew Ebden	2	3
								2	Cedrik-Marcel Stebe	5	1r
								6	Marc-Andrea Hüsler	7	1
		Teymuraz Gabashvili	4	4
	6	Marc-Andrea Hüsler	6	6

	First round							Qualifying competition
	3	Sumit Nagal	6	6
		Andrea Pellegrino	3	4
								3	Sumit Nagal	6	6
									Maxime Janvier	2	1
		Maxime Janvier	6	6
	7	Maxime Cressy	4	3

	First round							Qualifying competition
	4	Jurij Rodionov	6	77
	WC	Francesco Forti	4	64
								4	Jurij Rodionov	5	6	0
								8	Liam Broady	7	4	6
	WC	Jacopo Berrettini	4	1
	8	Liam Broady	6	6

• Main draw
• Qualifying draw