2021 Copa Colsanitas – Singles

Singles
2021 Copa Colsanitas
Champion	Camila Osorio
Runner-up	Tamara Zidanšek
Score	5–7, 6–3, 6–4
Draw	32
Seeds	8

Camila Osorio defeated Tamara Zidanšek in the final, 5–7, 6–3, 6–4 to win the singles tennis title at the 2021 Copa Colsanitas. It was the Colombian teenage wildcard's first WTA Tour singles title. Ranked No. 180, Osorio became the lowest-ranked WTA title holder since world No. 299 Margarita Gasparyan at the 2018 Tashkent Open. Zidanšek was also in contention for her first WTA title.^[1]

Amanda Anisimova was the reigning champion from when the tournament was last held in 2019,^[2] but chose to compete in Charleston instead.^[3]

	Semifinals							Final
	WC	Camila Osorio	6	6
	Q	Harmony Tan	1	2
								WC	Camila Osorio	5	6	6
								5	Tamara Zidanšek	7	3	4
		Viktoriya Tomova	3	5
	5	Tamara Zidanšek	6	7

	First round							Second round							Quarterfinals							Semifinals
	1	S Zheng	6	6
		UM Arconada	3	1				1	S Zheng	4	1
		S Vögele	3	6	6				S Vögele	6	6
	Q	C Paquet	6	1	4											S Vögele	3	5
	WC	C Osorio	6	6											WC	C Osorio	6	7
		S Vickery	3	2				WC	C Osorio	6	6
		L Küng	6	4	4			7	T Martincová	3	3
	7	T Martincová	4	6	6																	WC	C Osorio	6	6
	4	C Tauson	6	3	2																	Q	H Tan	1	2
	Q	D Seguel	3	6	6			Q	D Seguel	4	63
		M Buzărnescu	3	3				Q	H Tan	6	77
	Q	H Tan	6	6											Q	H Tan	6	6
	Q	L Arruabarrena	6	6											Q	L Arruabarrena	1	4
	WC	J Plazas	0	1				Q	L Arruabarrena	2	6	6
		K Ahn	3	0				6	J Paolini	6	4	2
	6	J Paolini	6	6

	First round							Second round							Quarterfinals							Semifinals
	8	Y Wang	6	5	7
	WC	E Arango	4	7	5			8	Y Wang	3	3
		A-L Friedsam	2	3					V Tomova	6	6
		V Tomova	6	6												V Tomova	5	6	6
		C Bucșa	3	2											Q	N Párrizas Díaz	7	2	4
	Q	N Párrizas Díaz	6	6				Q	N Párrizas Díaz	77	2	6
		I Bara	4	7	4			3	A Rus	64	6	1
	3	A Rus	6	5	6																		V Tomova	3	5
	5	T Zidanšek	6	7																		5	T Zidanšek	6	7
		A Kalinskaya	0	5				5	T Zidanšek	6	6
		A Sharma	6	5	1			Q	G Gatto-Monticone	2	3
	Q	G Gatto-Monticone	4	7	6										5	T Zidanšek	6	6
		AK Schmiedlová	4	6	1											S Errani	3	4
		A Bolsova	6	3	6				A Bolsova	4	4
		S Errani	7	7					S Errani	6	6
	2	S Sorribes Tormo	5	5

	First round							Qualifying competition
	1	Arina Rodionova	4	62
		Dalila Jakupović	6	77
									Dalila Jakupović	2	2
								7	Harmony Tan	6	6
		Yana Sizikova	1	6	4
	7	Harmony Tan	6	4	6

	First round							Qualifying competition
	2	Lara Arruabarrena	6	6
	PR	Carol Zhao	0	0
								2	Lara Arruabarrena	6	6
								WC	Yuliana Monroy	0	0
	WC	Yuliana Monroy	77	2	6
	10	Natalija Kostić	65	6	4

	First round							Qualifying competition
	3	Giulia Gatto-Monticone	6	6
	WC	Kelly Vargas González	3	0
								3	Giulia Gatto-Monticone	4	7	6
									Marie Benoît	6	5	3
		Marie Benoît	6	6
	8	Mariam Bolkvadze	4	0

	First round							Qualifying competition
	4	Nuria Párrizas Díaz	4	6	6
	WC	Mariana Manyoma	6	3	0
								4	Nuria Párrizas Díaz	77	4	6
								12	Marina Melnikova	62	6	1
		Katarzyna Piter	5	0
	12	Marina Melnikova	7	6

	First round							Qualifying competition
	5	Clara Burel	3	6	4
		Katharina Gerlach	6	1	6
									Katharina Gerlach	1	1
									Daniela Seguel	6	6
		Daniela Seguel	6	6
	11	Danielle Lao	1	2

	First round							Qualifying competition
	6	Chloé Paquet	6	6
	WC	Antonia Samudio	2	3
								6	Chloé Paquet	3	6	6
								9	Robin Anderson	6	3	2
		Paula Kania-Choduń	1	4
	9	Robin Anderson	6	6

• Main Draw
• Qualifying Draw