2021 Australian Open – Wheelchair women's singles
| Wheelchair women's singles | |
|---|---|
| 2021 Australian Open | |
| Champion |  Diede de Groot |
| Runner-up |  Yui Kamiji |
| Score | 6–3, 6–7(4–7), 7–6(10–4) |
| Draw | 8 |
| Seeds | 2 |
Diede de Groot defeated the defending champion Yui Kamiji in the final, 6–3, 6–7(4–7), 7–6(10–4) to win the women's singles wheelchair tennis title at the 2021 Australian Open. It was the first step in an eventual Super Slam for de Groot.
Seeds
- Diede de Groot (champion)
- Yui Kamiji (final)
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- ITF = ITF entry
- PR = Protected ranking
- SR = Special ranking
- SE = Special exempt
- JE = Junior exempt
- JR = Junior Accelerator Programme entrant
- CO = College Accelerator Programme entrant
- NG = Next Gen Accelerator Program entrant
- w/o = Walkover
- r = Retired
- d = Defaulted
Bracket
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 3 | 6 | ||||||||||||||||
| Aniek van Koot
| 0 | 6 | 4 | |||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| Momoko Ohtani
| 2 | 4 | ||||||||||||||||||
| Momoko Ohtani
| 6 | 6 | ||||||||||||||||||
 Lucy Shuker
| 2 | 2 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 64 | 710 | ||||||||||||||||
| 2 | Yui Kamiji
| 3 | 77 | 64 | ||||||||||||||||
 Angélica Bernal
| 1 | 2 | ||||||||||||||||||
 Kgothatso Montjane
| 6 | 6 | ||||||||||||||||||
| Kgothatso Montjane
| 1 | 7 | 0 | |||||||||||||||||
| 2 | Yui Kamiji
| 6 | 5 | 6 | ||||||||||||||||
 Macarena Cabrillana
| 0 | 1 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 6 | |||||||||||||||||