2018 US Open – Wheelchair women's singles
| Wheelchair women's singles | |
|---|---|
| 2018 US Open | |
| Champion |  Diede de Groot |
| Runner-up |  Yui Kamiji |
| Score | 6–2, 6–3 |
Diede de Groot defeated the defending champion Yui Kamiji in a rematch of the previous year's final, 6–2, 6–3 to win the women's singles wheelchair tennis title at the 2018 US Open. It was her first US Open singles title, and was her second step towards a non-calendar-year Grand Slam.
Seeds
- Diede de Groot (champion)
- Yui Kamiji (final)
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- ITF = ITF entry
- PR = Protected ranking
- SR = Special ranking
- SE = Special exempt
- JE = Junior exempt
- JR = Junior Accelerator Programme entrant
- CO = College Accelerator Programme entrant
- NG = Next Gen Accelerator Program entrant
- w/o = Walkover
- r = Retired
- d = Defaulted
Bracket
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| Aniek van Koot
| 1 | 2 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
 Sabine Ellerbrock
| 0 | 3 | ||||||||||||||||||
| WC |  Dana Mathewson
| 1 | 2 | |||||||||||||||||
| Sabine Ellerbrock
| 6 | 6 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| 2 | Yui Kamiji
| 2 | 3 | |||||||||||||||||
 Kgothatso Montjane
| 6 | 6 | ||||||||||||||||||
 Lucy Shuker
| 4 | 4 | ||||||||||||||||||
| Kgothatso Montjane
| 1 | 0 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 6 | |||||||||||||||||
| Marjolein Buis
| 0 | 0 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 6 | |||||||||||||||||